Expression of p14ARF, p15INK4b, p16INK4a, and DCR2 increases during prostate cancer progression
نویسندگان
چکیده
منابع مشابه
Mutational analysis of genes p14ARF, p15INK4b, p16INK4a, and PTEN in human nervous system tumors.
Cancer is one of the most common and severe problems in clinical medicine, and nervous system tumors represent about 2% of the types of cancer. The central role of the nervous system in the maintenance of vital activities and the functional consequences of the loss of neurons can explain how severe brain cancers are. The cell cycle is a highly complex process, with a wide number of regulatory p...
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متن کاملDifferential expression of osteonectin/SPARC during human prostate cancer progression.
The precise mechanism(s) involved in invasion and metastasis of prostate cancer (CaP) is poorly understood. Osteonectin [ON (also known as SPARC or BM-40)] is an antiadhesive protein known to be involved in cell-matrix interactions, migration, and angiogenesis. In this report, we studied the expression of ON in human prostate cell lines, primary tumors, and metastatic foci of CaP. Reverse trans...
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ژورنال
عنوان ژورنال: Modern Pathology
سال: 2006
ISSN: 0893-3952,1530-0285
DOI: 10.1038/modpathol.3800655